ea0015oc16 | Reproduction | SFEBES2008
Vassiliadi Dimitra A
, Tomlinson Jeremy W
, Hughes Beverly A
, Gay Christopher
, Sira Shaleen
, Nightingale Peter
, Shackleton Cedric HL
, Stewart Paul M
, Arlt Wiebke
Polycystic ovary syndrome (PCOS) affects 510% of the female population. It is characterised by androgen excess and anovulatory infertility; several studies have reported an increased incidence of the metabolic syndrome and enhanced 5α-reductase activity in PCOS. However, the contribution of obesity to these findings has yet to be clarified. Here we have analysed metabolic status and urinary steroid metabolite excretion in 114 patients with PCOS (median age 30 (range...